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USC vs. Notre Dame predictions, odds, line: 2022 Week 13 College Football picks, best bets by proven model

USC vs. Notre Dame predictions, odds, line: 2022 Week 13 College Football picks, best bets by proven model

The contenders face off at Los Angeles Memorial Coliseum on Saturday night. The USC No. 6 Trojans host the No. 15 Notre Dame Fighting Irish in both programs’ regular season finale. Notre Dame is 8-3 and on a four-game winning streak. USC is 10-1 overall and 6-0 at home, with an appearance in the Pac-12 Championship Game next week.

Kick-off time is 7:30 PM ET in Los Angeles. Caesars Sportsbook lists the Trojans as a 5-point home favorite, while the over/under count, or the total number of points Vegas thinks will be scored, is 64.5 in Notre Dame’s latest odds vs. USC. Before making any USC vs. Notre Dame selections, be sure to check out our college football predictions and betting tips from SportsLine’s installed computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six years, the proprietary computer model has generated an astounding profit of nearly $3,000 per player’s $100 on top-ranked college football picks for the difference. Anyone who has followed it has seen huge returns.

Now, the model has set his sights on USC vs. Notre Dame and just revealed his picks and CFB predictions. You can visit SportsLine now to see the exhibitors’ picks. Now, here are several college football odds and trends for the Notre Dame-USC matchup:

  • Notre Dame vs. USC spread: USC -5
  • Notre Dame vs. USC over/under: 64.5 points
  • Notre Dame vs. USC money line: USC -210, ND +175
  • ND: The Irish are 6-5 against the spread this season
  • USC: The Trojans are 7-4 against the spread this season
  • Notre Dame vs. USC picks: See picks at SportsLine

Featured game | USC Trojans vs. Notre Dame Fighting Irish

Why would you cover Notre Dame?

Notre Dame has the superior defense in this game. The Fighting Irish, led by Marcus Freeman, allow just 20.3 points per game, and Notre Dame is among the top 20 FBS players in total yards allowed (317.2 per game). Notre Dame is above average for passing and running backs, with the Irish giving up less than 190 yards per game. Opponents completed just 56.5% of pass attempts against Notre Dame, as the Fighting Irish produced 33 sacks, the 15th highest mark in the country.

Freshman defensive lineman Isaiah Foskey is in the top 10 in the FBS with 9.5 sacks, and Notre Dame is holding opponents with a low efficiency rating of 34%. On the other hand, USC allows 405 total yards per game, including 257.8 yards per contest, and the Trojans give up 4.6 yards per carry.

Why USC can be covered

USC is absolutely rolling on offense this season, leading a potential path to the College Football Playoff. The Trojans are averaging 42.9 points per game, which is #3 among FBS teams this season. USC has scored 40 or more points in five straight games, and the Trojans have a school record with nine games with at least 40 points. The Trojans are No. 2 in the nation at 513.0 total yards per game, and USC is No. 4 in the country in passing offense, yielding 330.8 yards per game through the air.

USC is in the top ten in the country with 9.1 yards per pass attempt, and the team has 34 touchdown passes and only three interceptions this season. Caleb Williams is a Heisman Trophy candidate at quarterback, and USC also plays a solid running game. The Trojans average 182.2 rushing yards per game, a top five mark in the Pac-12, and USC averages 5.3 rushing yards per carry. In addition to blasting, USC is a high efficiency scorer with the No. 2 mark in the nation in third at an efficiency drop of 54.3%.

How to make USC versus Notre Dame picks

SportsLine’s model tends to be less than the total, and expects teams to combine for 61 points. The model also says that one side of the spread is up more than 50% of the time. You only get to choose the model at SportsLine.

So who will win Notre Dame versus USC? And which side of the spread is up more than 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from form crushing college football picks, and find out.



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